OLIVE OIL PREVENT HYPERTENSION
Researchers have said that a diet that combines unsaturated fats
with nitrite-rich vegetables, like olive oil and lettuce, could help protect
you from hypertension.
The Mediterranean diet typically includes unsaturated fats found
in olive oil, nuts and avocados, along with vegetables like spinach, celery and
carrots that are rich in nitrites and nitrates.
When these two food groups are combined, the reaction of unsaturated
fatty acids with nitrogen compounds in the vegetables results in the formation
of nitro fatty acids.
The study, supported by the British Heart Foundation, used mice
to investigate the process by which these nitro fatty acids lower blood
pressure, looking at whether they inhibited an enzyme known as soluble Epoxide
Hydrolase which regulates blood pressure.
Mice genetically engineered to be resistant to this inhibitory
process were found to maintain their high blood pressure despite being fed the
type of nitro fatty acids that normally form when a Mediterranean diet is
consumed. However, nitro fatty acids were found to lower the blood pressure of
normal mice following the same diets.
Thus, the study concludes that the protective effect of the
Mediterranean diet, combining unsaturated fats and vegetables abundant in
nitrite and nitrate, comes at least in part from the nitro fatty acids
generated which inhibit soluble Epoxide Hydrolase to lower blood pressure.
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