CARBONATED DRINKS LINKED WITH OUT -OF - HOSPITAL CARDIAC ARREST OF CARDIAC ORIGIN
Carbonated beverages are associated with
out-of-hospital cardiac arrests of cardiac origin, according to results from
the All-Japan Utstein Registry presented for the first time today at ESC
Congress. The study in nearly 800,000 patients suggests that limiting
consumption of carbonated beverages may be beneficial for health.
"Some
epidemiologic studies have shown a positive correlation between the consumption
of soft drinks and the incidence of cardiovascular disease (CVD) and stroke,
while other reports have demonstrated that the intake of green tea and coffee
reduced the risk and mortality of CVD," said principal investigator
Professor Keijiro Saku, Dean and professor of cardiology at Fukuoka University
in Japan. "Carbonated beverages, or sodas, have frequently been
demonstrated to increase the risk of metabolic syndrome and CVD, such as
subclinical cardiac remodeling and stroke. However, until now the association
between drinking large amounts of carbonated beverages and fatal CVD, or
out-of-hospital cardiac arrests (OHCA) of cardiac origin, was unclear."
The study compared the
age-adjusted incidence of OHCAs to the consumption of various beverages per
person between 2005 and 2011 in the 47 prefectures of Japan. It included 797
422 patients who had OHCAs of cardiac and non-cardiac origin from the All-Japan
Utstein Registry of the Fire and Disaster Management Agency. Data on the
consumption of the various beverages per person was obtained from the Ministry
of Health, Labour and Welfare of Japan, using expenditure on beverages as a
proxy measure.
The analysis focused on
the 785 591 OHCA cases that received resuscitation, of which 435 064 (55.4%)
were of cardiac origin and 350 527 (44.6%) were of non-cardiac origin. Those of
non-cardiac origin included cerebrovascular disease, respiratory disease,
malignant tumour, and exogenous disease (4.8%, 6.1%, 3.5%, and 18.9%,
respectively).
The researchers found
that expenditures on carbonated beverages were significantly associated with
OHCAs of cardiac (r=0.30, p=0.04), but not non-cardiac origin (r=-0.03, p=0.8).
Expenditures on other
beverages, including green tea, black tea, coffee, cocoa, fruit or vegetable
juice, fermented milk beverage, milk and mineral water were not significantly
associated with OHCAs of cardiac origin.
"Carbonated beverage
consumption was significantly and positively associated with OHCAs of cardiac
origin in Japan, indicating that beverage habits may have an impact on fatal
CVD," said Professor Saku. "The acid in carbonated beverages might
play an important role in this association."
Professor Saku concluded:
"Our data on carbonated beverage consumption is based on expenditure and
the association with OHCA is not causal. But the findings do indicate that
limiting consumption of carbonated beverages could be beneficial for
health."
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