UTERINE CONTRACTIONS INCREASE SUCCESS OF ARTIFICIAL INSEMINATION
The negative impact of
contractions during in vitro fertilization is a well-known fact. What was
unknown until now was the effect it had on artificial insemination. A new study
has discovered that it is the contrary to that seen in embryo transfer: there
is an improved chance of getting pregnant.
Researchers from the
Valencian Infertility Institute (IVI) have demonstrated that the number of
contractions of the uterus per minute is a parameter associated with success in
artificial insemination procedures.
The study, recently
published in the journal Fertility & Sterility, has been
carried over the course of five years with data obtained from a sample of over
600 women.
"The number of
uterine contractions per minute is positively related to the rate of clinical
pregnancy and that of live births following artificial insemination, with the
correct synchronisation of the moment of insemination being especially important,"
explains Manuel Fernández, the main author of the work and director of the IVI
in Seville.
Additionally, as
Fernández says: "When the number of contractions is high, the rates of
pregnancy and live births are also notably elevated".
Artificial
insemination is, according to experts, one of the assisted reproduction
techniques that has developed the least during recent years, as it has lost
importance in favor of other more complex techniques that have higher success
rates per cycle.
It is one of the most
physiological and widely used assisted reproduction procedures, due to its low
complexity. The data supports the idea that this technique has a success rate
of 15-20% per cycle if it is carried out with the partner's sperm and 25% if it
is carried out with a donor's sperm.
Predictors of the live
birth rate
In the study, other
predicting variables that are independent of the rate of live births following
artificial insemination have also been detected: type of insemination treatment
(sperm of partner or donor), maternal age and number of follicles.
"We have observed
that synchronizing the day of insemination with the moment of the follicular
rupture (when the egg is released) is key to improving the results of this kind
of treatment. If we manage to improve artificial insemination success rates
using this and other studies, we would be contributing to an important advance,
given that this is currently the most accessible and widely used
treatment," concludes Fernández.
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