SCIENTISTS REVEAL HOW LUNG CANCER SPREADS
Scientists have revealed the mystery behind
spreading of lung cancer.
The
researchers at the Cancer Research UK Manchester Institute discovered that the
ties which lash cells together - controlled by a protein called TIAM1 - were
chopped up when cell maintenance work goes wrong.
Healthy
cells routinely scrap old cell parts so they could be broken down and used
again. But this process spiraled out of control in lung cancer cells, which
scraped too many TIAM1 ties.
Targeting
this recycling process could stop lung cancer from spreading by keeping the
cells stuck firmly together.
Lead
researcher, Dr Angeliki Malliri, at the Cancer Research UK Manchester Institute
at the University of Manchester, said that the research showed for the first time
how lung cancer cells severed ties with their neighbours and start to spread
around the body, by hijacking the cells' recycling process and sending it into
overdrive. Targeting this flaw could help stop lung cancer from spreading.
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